Olanzapine and amenorrhea
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چکیده
Until 27 April 2006, the Netherlands Pharmacovigilance Centre Lareb received 7 reports of amenorrhea associated with the use of olanzapine. The time to onset varies from a few weeks to 10 months. The outcome was reported in 3 cases. One patient recovered after drug withdrawal and two patients did not recover; in one patient there was a dose increase to 15 mg once daily. In case D, hyperprolactinaemia (1150 mU/L, range 50-629 mU/L) was also reported. Benzodiazepine was used as concomitant medication in 4 of the 7 patients.
منابع مشابه
Clinical consequences of switching from olanzapine to risperidone and vice versa in outpatients with schizophrenia: 36-month results from the worldwide schizophrenia outpatients health outcomes (W-SOHO) study
BACKGROUND With many atypical antipsychotics now available in the market, it has become a common clinical practice to switch between atypical agents as a means of achieving the best clinical outcomes. This study aimed to examine the impact of switching from olanzapine to risperidone and vice versa on clinical status and tolerability outcomes in outpatients with schizophrenia in a naturalistic s...
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